Implication of region-dependent material properties of articular cartilage in the contact mechanics of porcine knee joint.

ABSTRACT:

Background

The site-specific tissue properties of knee cartilage may play an essential role in knee joint mechanical function, and mitigate joint injury and cartilage degeneration. The present study aimed to determine the significance of tissue inhomogeneity in knee joint contact mechanics using a porcine model.

Methods

Finite element models were developed for a porcine knee with intact and total meniscectomy conditions to simulate whole-joint compression-relaxation tests under a 1.2-mm ramp-compression at 0.01, 0.1, or 1 mm/s. Two reference benchmarks were introduced for the implementation of poromechanical material properties of fibril-reinforced cartilage: Benchmark II consisted of 17 sets of cartilage properties, each for a region in the knee, representing site-specific

SUBMITTER: Hamsayeh Abbasi Niasar E 

PROVIDER: S-EPMC11827382 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature