Safety of transarterial chemoembolization on renal function in combined hepatocellular carcinoma and chronic kidney disease patients.

ABSTRACT: This study was to investigate the safety of transarterial chemoembolization (TACE) which required injection of contrast medium on renal function in combined hepatocellular carcinoma and chronic kidney disease (CKD) patients. A total of 265 patients admitted for the first session of TACE were included for analysis. CKD was defined as Cockcroft-Gault glomerular filtration rate (CG-GFR) < 60 mL/min/1.73 m². The odds ratio (OR) and 95% confident interval (CI) were calculated to show the influence of factors on renal function. Overall, 24.07% patients with CKD and 31.21% patients without CKD showed exacerbated renal function at discharge. However, 73.15% patients with CKD and 63.69% patients without CKD showed significantly improved renal function (all p = 0.00001). No significant di

SUBMITTER: Lin ZY 

PROVIDER: S-EPMC11827540 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature