OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis.

ABSTRACT:

Purpose

To explore the relationship between visual performance and retinal morphology as assessed by optical coherence tomography (OCT), and the ability of OCT to reflect visual impairment in people with multiple sclerosis (PwMS) compared with healthy controls (HC).

Methods

We gathered data from two neurology referral centers on PwMS and HC. Neurological and ophthalmological assessments, including OCT, high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA), area under the log contrast sensitivity function (AULCSF), and vision-related quality of life (National Eye Institute Visual Function Questionnaire), were conducted between 2018 and 2020, with follow-up at 1 year.

Results

A total of 137 PwMS (271 eyes) and 118 HC (236 eyes) were available for anal

SUBMITTER: Stolowy N 

PROVIDER: S-EPMC11827617 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature