Refractive Development and Choroidal Vascularity in the Form-Deprivation Pigmented Rabbit Model.

ABSTRACT:

Purpose

This study assessed the characteristics of refractive development and choroidal vasculature in the form-deprivation (FD) pigmented rabbit model.

Methods

Monocular FD was performed in three-week-old pigmented rabbits (n = 18 for FD, n = 12 for control). Throughout the eight-week rearing period, refractive errors, corneal curvature radius (CCR), ocular biometric parameters, retinal thickness (RT), and choroidal thickness (ChT) were measured every two weeks using cycloplegic retinoscopy, keratometer, A-scan ultrasonography, and optical coherence tomography (OCT). The choroidal vascularity index (CVI) was calculated from OCT images by measuring the total choroidal area (TCA), stromal area (SA), and luminal area (LA). At the end of the form deprivation, the vitreous dopam

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC11827862 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature