Global burden of thyroid cancer in adolescents and young adults (aged 15-39 years) from 1990 to 2021: A systematic analysis of the Global Burden of Disease Study 2021.

ABSTRACT:

Background

Thyroid cancer (TC) is the most common malignancy of the endocrine system and head-and-neck region, yet data on its burden in adolescents and young adults (AYAs) is lacking. This study aimed to estimate the global burden of TC among AYAs from 1990 to 2021.

Methods

Utilizing the Global Burden of Disease (GBD) 2021 data, we analyzed age-standardized rates of incidence, prevalence, and disability-adjusted life-years (DALYs) on global, regional, and national scales. Joinpoint regression was employed to determine average annual percentage change (AAPC), with frontier analysis revealing regions for improvement. Decomposition analysis assessed the impacts of population aging, growth, and epidemiological changes. Projections for disease burden extending to 2040 were gener

SUBMITTER: Qiu Z 

PROVIDER: S-EPMC11828416 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature