The Bidirectional Relationship Between Iron Deficiency Anemia and Chronic Headache Disorders: A Systematic Review and Meta-Analysis.

ABSTRACT: Background and Objective: IDA and chronic headache disorders such as migraines and tension-type headaches are common conditions that significantly affect quality of life. Emerging evidence suggests a bidirectional relationship between these two conditions. This systematic review and meta-analysis aimed to explore and quantify the association between iron deficiency anemia (IDA) and chronic headache disorders, with a focus on understanding the bidirectional nature of this relationship. Methods: A comprehensive literature search was conducted across PubMed, Embase, and Web of Science to identify relevant studies published up until August 10, 2024. Observational studies examining the prevalence, incidence, or association between IDA and chronic headache disorders were included.

SUBMITTER: Rohilla S 

PROVIDER: S-EPMC11828653 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature