Meconium-Related Obstruction and Clinical Outcomes in Term and Preterm Infants.

ABSTRACT:

Importance

Textbooks attribute 80% of meconium-related small bowel obstructions to cystic fibrosis and 15% of colonic obstructions to Hirschsprung disease. It is unknown whether these estimates are accurate, particularly among preterm infants, whose immature bowel predisposes them to meconium-related obstruction (MRO).

Objective

To estimate the incidence of MRO by type and to assess its association with clinical outcomes.

Design, setting, and participants

This retrospective cohort study of live-born infants included in the National Inpatient Sample from January 1, 2016, to December 31, 2020, used survey weighting methods to estimate the national incidence of MRO by etiology. Data were analyzed from November 27, 2023, to November 12, 2024.

Exposure

MRO.

Main

SUBMITTER: Rook JM 

PROVIDER: S-EPMC11829230 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature