Racial and Ethnic Survival Disparities Among Children With High-Risk Neuroblastoma: A Children's Oncology Group Report.

ABSTRACT:

Importance

Whether population-based racial and ethnic survival disparities for children with high-risk neuroblastoma persist in the clinical trial setting is unknown.

Objective

To investigate racial and ethnic survival disparities among children with high-risk neuroblastoma treated on frontline clinical trials.

Design, setting, and participants

This retrospective cohort study used data from Children's Oncology Group (COG) high-risk neuroblastoma trials from January 1, 2007, to December 31, 2016, with a data freeze on June 30, 2021. Children with high-risk neuroblastoma were analyzed in 2 cohorts: induction/consolidation trial participants and post-consolidation trial participants. Statistical analyses were performed from September 2, 2021, to December 30, 2024.

Exp

SUBMITTER: Umaretiya PJ 

PROVIDER: S-EPMC11829236 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature