Associations of the gut, cervical, and vaginal microbiota with cervical cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

An increasing number of studies indicate that the gut, cervical, and vaginal microbiota may play crucial roles in the development of cervical cancer (CC). However, the interactions between the microbiota and the host are yet unknown. To address this gap, a systematic review and meta-analysis were conducted to assess the microbiota alterations in a variety of body locations, including the gut and genital tract.

Methods

Electronic searches of PubMed, Embase, Web of Science, and the Cochrane Library were conducted to retrieve eligible papers published from January 1, 2014, to January 1, 2024 (PROSPERO: CRD42024554433). This study was restricted to English-language studies reporting on alpha diversity, beta diversity, and relative abundance, as well as on patients wit

SUBMITTER: Wen Q 

PROVIDER: S-EPMC11829412 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature