Joint association of systemic inflammatory response index and sarcopenia with mortality among individuals with self-reported cancer.

ABSTRACT:

Purpose

The aim of this study was to investigate the joint association of systemic inflammatory response index (SIRI) and sarcopenia with cancer-specific and all-cause mortality in individuals with self-reported cancer.

Methods

The study cohort comprised individuals with a self-reported cancer diagnosis from the NHANES database, with data collected between 1999 and 2006 and 2011-2018. The researchers tracked deaths up to 31 December 2019 by linking the relevant records to those held by the (NDI). A weighted sampling design was employed, with participants stratified according to the median value of the SIRI. Cox regression models were employed to assess the association between SIRI, sarcopenia, all-cause mortality, and cancer-specific mortality.

Results

The study cohor

SUBMITTER: Huang Z 

PROVIDER: S-EPMC11829532 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature