The effects of exercise, heat-induced hypo-hydration and rehydration on blood-brain-barrier permeability, corticospinal and peripheral excitability.

ABSTRACT:

Purpose

The effects of low-intensity exercise, heat-induced hypo-hydration and rehydration on maximal strength and the underlying neurophysiological mechanisms are not well understood.

Methods

To assess this, 12 participants took part in a randomised crossover study, in a prolonged (3 h) submaximal (60 W) cycling protocol under 3 conditions: (i) in 45 °C (achieving ~ 5% body mass reduction), with post-exercise rehydration in 2 h (RHY2), (ii) with rehydration across 24 h (RHY24), and (iii) a euhydrated trial in 25 °C (CON). Dependent variables included maximal voluntary contractions (MVC), maximum motor unit potential (M_MAX), motor evoked potential (MEP_RAW) amplitude and cortical silent period (cSP) duration. Blood-brain-barrier integrity was also assess

SUBMITTER: Uddin N 

PROVIDER: S-EPMC11829906 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature