Endoscopic and pathological characteristics of gastrointestinal amyloidosis: a retrospective analysis.

ABSTRACT:

Background

Gastrointestinal amyloidosis (GIA) is a rare manifestation of amyloidosis, characterized by amyloid fibril deposition in the gastrointestinal tract, leading to a range of clinical symptoms. Early diagnosis is challenging due to the nonspecific nature of endoscopic and clinical findings.

Objective

To analyze the clinical, endoscopic, and pathological characteristics of GIA and identify potential diagnostic markers for earlier detection.

Methods

A retrospective study was conducted on 36 patients diagnosed with GIA based on histopathological findings, including Congo Red staining. Clinical, endoscopic, and pathological data were analyzed to identify correlations between lesion morphology, clinical symptoms, and amyloid deposition.

Results

The cohort con

SUBMITTER: Niu Z 

PROVIDER: S-EPMC11830184 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature