Proteomic analysis emphasizes the adaptation of energy metabolism in horses during endurance races.

ABSTRACT:

Background

Long-term aerobic exercise during endurance racing places high demands on equine homeostasis. This study aimed to use proteomic analysis to elucidate complex biological responses during endurance exercise. It was hypothesized that different serum proteome changes would be noted, reflecting physiological processes as a response to race. The serum has been taken before and after an 80 km race from 13 endurance horses. Proteomic analysis of samples has been performed by TMT-based quantitative method. Apolipoprotein and haptoglobin values have been validated by enzyme-linked immunosorbent assay and biochemical assay respectively. The difference in protein abundance between pre and post-race values has been determined.

Results

In serum samples, 10 master proteins with

SUBMITTER: Gotic J 

PROVIDER: S-EPMC11830206 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature