World Health Organization priority antimicrobial resistance in <i>Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus</i> and <i>Enterococcus faecium</i> healthcare-associated bloodstream infections in Brazil (ASCENSION): a prospective, multicentre, observational study.

ABSTRACT:

Background

Carbapenem-resistant Enterobacterales (CRE), Acinetobacter baumannii (CRAB), Pseudomonas aeruginosa (CRPA), methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VRE) are listed by World Health Organization (WHO) as priority antimicrobial-resistant bacteria. Data on WHO Priority Antimicrobial resistance Phenotype (WPAP) bacteria from low- and middle-income countries are scarce. In this study, we investigated the occurrence of WPAP in healthcare-associated bloodstream infections (BSI) in Brazil, an upper-middle-income country in South America.

Methods

ASCENSION was a prospective, multicentre, observational study conducted in 14 hospitals from four of five Brazilian regions. Enterobact

SUBMITTER: Antochevis LC 

PROVIDER: S-EPMC11830303 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature