<i>Legionella</i> <i>pneumophila</i> response to shifts in biofilm structure mediated by hydrodynamics.

ABSTRACT: Preventing legionellosis in water systems demands effective hydrodynamic management and biofilm mitigation. This study investigates the complex relationship between hydrodynamics (80 RPM and stagnation), biofilm mesoscale structure and Legionella pneumophila colonization, by addressing three key questions: (1) How do low flow vs stagnation conditions affect biofilm response to L. pneumophila colonization?, (2) How do biofilm structural variations mediate L. pneumophila migration across the biofilm?, and (3) Can specific hydrodynamic conditions trigger L. pneumophila entrance in a viable but nonculturable (VBNC) state? It was found that Pseudomonas fluorescens biofilms exhibit different responses to L. pneumophila based on the prevailing hydr

SUBMITTER: Silva AR 

PROVIDER: S-EPMC11830327 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature