Incidence and temporal patterns of true recurrences and second primaries in women with breast cancer: A 10-year competing risk-adjusted analysis.

ABSTRACT:

Introduction

We report a population-based, competing risk-adjusted analysis of the risk and timing of true recurrences and second primaries in women with breast cancer (BC), that are still ill-defined.

Methods

We performed a manual review of medical charts of 1988 BC patients from a cancer registry in northern Italy (2000-2013). The occurrence and timing of true recurrences (TRs, including local, regional and distant recurrences) and second BCs (SBCs, including ipsilateral and contralateral SBC) during 10 years of follow-up were evaluated. The prognostic factors for TRs and SBCs were identified using the Fine and Gray model.

Results

The cumulative incidence was 13.7 % (95 % confidence interval (CI), 12.2-15.3 %) for TRs and 4.6 % (95 % CI, 3.7-5.7 %) for SBCs. The med

SUBMITTER: Mancini S 

PROVIDER: S-EPMC11830374 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature