Comparison of Al[¹⁸F]-NOTA-FAPI-04 PET/CT and [¹⁸F]-FDG PET/CT in a patient with lung cancer and pulmonary tuberculosis: a case report and literature review.

ABSTRACT:

Background

The coexistence of lung cancer and pulmonary tuberculosis (TB) makes differential diagnosis even more complicated. The purpose of the study is to explore superiority of [¹⁸F]-NOTA-FAPI-04 PET/CT in distinguishing TB from malignant lesions and accurately detecting inflammatory lymph nodes than [¹⁸F]-FDG PET/CT.

Case summary

Herein, we described a case report of a patient with both lung cancer and tuberculosis underwent [¹⁸F]-FDG and Al[¹⁸F]-NOTA-FAPI-04 positron emission tomography/computed tomography (PET/CT) to determine staging. Additionally, a literature review was conducted to discuss the potential clinical applications of FAPI PET/CT. We reported a 70-year-old man with newly diagnosed lung squamous cell carcinoma un

SUBMITTER: Qin J 

PROVIDER: S-EPMC11830580 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature