Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study.

ABSTRACT:

Objective

Kidney stones are a major issue for public health worldwide. Discovering potential clues in identifying at-risk individuals is essential for early detection and timely treatment. This study explores the relationship of the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) with the risk of kidney stones in U.S. adults.

Methods

The analysis involved 24,532 participants with available NHR and kidney stone data from the 2007-2018 NHANES period. Multivariable logistic regression models were used to quantify the relationship between NHR and kidney stone occurrence. Subgroup analyses were conducted to explore variations in effect.

Results

A total of 2,351 participants (9.93%) were diagnosed with kidney stones, and their mean age was 47.20 ± 0.26 years.

SUBMITTER: Du YZ 

PROVIDER: S-EPMC11830614 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature