Bacterial blood microbiome of <i>Mastomys</i> rodents: implications for disease spill-over at the animal-human interface within the Bushbuckridge-East community, South Africa.

ABSTRACT: The Bushbuckridge-East community in Mpumalanga Province, South Africa is bordered by nature reserves, including the Manyeleti Game Reserve. Murid rodents are prevalent in both Manyeleti and communal rangelands adjoining the community households. Although rodents are reservoir hosts for a broad range of viral, bacterial and parasitic pathogens, the rodent microbial diversity and transmission of zoonotic agents to humans in the community is understudied. In this study we investigated bacterial diversity in wild and commensal rodents sampled from different habitats. The 16S rRNA gene was amplified from DNA extracted from the blood of 24 wild Mastomys and one Steatomys sp. and subjected to PacBio circular consensus sequencing. As Bartonella species were dominant in the blo

SUBMITTER: Kolo AO 

PROVIDER: S-EPMC11830667 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature