Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women.

ABSTRACT:

Objective

Currently, it has been reported that uterine microbiota affected pregnancy outcomes in assisted reproductive technology, but little was known in obese women. Thus, this study aims to explore how body weight affects pregnancy outcomes by comparing the differences in uterine microbiota between women of normal weight and those with obesity or overweight.

Methods

The study included 45 embryo transfer cycles. Patients were divided into two groups based on body mass index (BMI): normal-weight group, BMI ≤23.9 kg/m² (Con group, n=31) and obesity/overweight group, BMI >23.9 kg/m² (OwOb group, n=14). Microbial samples were collected from the catheter tips and analyzed using RNA Ribosomal 16S.

Results

In 45 women, the β-human chorionic gonadotropin (β-hCG) positivity

SUBMITTER: Yan Y 

PROVIDER: S-EPMC11830673 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature