How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials.

ABSTRACT:

Objective

To determine the effect of perioperative beta blocker treatment in patients having non-cardiac surgery.

Design

Systematic review and meta-analysis.

Data sources

Seven search strategies, including searching two bibliographic databases and hand searching seven medical journals. STUDY SELECTION AND OUTCOMES: We included randomised controlled trials that evaluated beta blocker treatment in patients having non-cardiac surgery. Perioperative outcomes within 30 days of surgery included total mortality, cardiovascular mortality, non-fatal myocardial infarction, non-fatal cardiac arrest, non-fatal stroke, congestive heart failure, hypotension needing treatment, bradycardia needing treatment, and bronchospasm.

Results

Twenty two trials that randomised a total o

SUBMITTER: Devereaux PJ 

PROVIDER: S-EPMC1183126 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature