Fabrication of Polydopamine-Coated High-Entropy MXene Nanosheets for Targeted Photothermal Anticancer Therapy.

ABSTRACT: Transition metal carbides, nitrides, and carbonitrides (MXenes) have emerged as a promising class of 2D materials that can be used for various applications. Recently, a new form of high-entropy MXenes has been reported, which contains an increased number of elemental species that can increase the configurational entropy and reduce the Gibbs free energy. The unique structure and composition lead to a range of intriguing and tunable characteristics. Herein, the fabrication of high-entropy MXene TiVNbMoC₃T_x (T = surface terminations) with a layer of polydopamine is reported, followed by immobilization of a phthalocyanine-based fluorophore for imaging and the peptide sequence QRHKPREGGGSC for targeting the epidermal growth factor receptor (EGFR) overexpressed in cancer ce

SUBMITTER: Zou Q 

PROVIDER: S-EPMC11831489 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature