Immunomodulatory and growth-promoting effects of <i>Rauwolfia serpentina</i> root powder in broiler chicks challenged with <i>Salmonella</i> Gallinarum.

ABSTRACT:

Background

Amid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. This study investigates the effects of ethnoveterinary supplementation of Rauwolfia serpentina (L. Benth. ex Kurz) powder (RSP) on three key immune-related genes; Suppressor of cytokine signaling 3 (SOCS3), the quiescence-related gene P20K (P20K), and the major histocompatibility complex Class IIβ (MHC class IIβ), gut morphology and growth performance of broiler chicks infected with Salmonella Gallinarum.

Methods

Two hundred and forty day-old Hubbard classic chickens were randomly assigned to four groups: non-challenged control (NC), and Salmonella<

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11831699 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature