Association between the new TyG indicator-TyHGB and gestational diabetes mellitus: results from the case-control and prospective cohort studies.

ABSTRACT:

Background

Given the close relationship between lipids and gestational diabetes mellitus(GDM), the present study sought to examine the association between the triglyceride high-density cholesterol-glucose body index(TyHGB) and the risk of developing GDM.

Methods

In order to investigate the relationship between TyHGB and GDM, a retrospective case-control study and a prospective cohort study were conducted involving 1862 individuals. A multifactorial logistic regression model was employed to assess the relationship between TyHGB and GDM, and to reduce potential bias and confounding variables, the association between TyHGB and GDM was evaluated using 1:1 propensity score further matching (PSM) multivariate logistic regression of post-PSM data. The restricted cubic splines(RCS)

SUBMITTER: Xu Z 

PROVIDER: S-EPMC11831843 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature