Diurnal changes of corneal epithelial and stromal thickness maps and visual quality in mild form of Fuchs' endothelial corneal dystrophy.

ABSTRACT:

Purpose

To investigate the functional and structural daily variations in eyes with a mild form of Fuchs' endothelial corneal dystrophy (FECD).

Methods

This prospective study included 30 eyes with the mild form of FECD. Subjects underwent functional and structural testing at 8 AM, 2 PM, and 8 PM. Testing included measurement of uncorrected distance visual acuity (UDVA), best corrected twilight vision (TV), and contrast sensitivity function (CSF) testing (Vista Vision Far-Pola, DMD MedTech charts). Corneal epithelial and stromal parameters were evaluated with anterior segment optical coherence tomography (AngioVue, AvantiRTVue-XR; Optovue, CA, USA).

Results

UDVA, TV, and CSF for spatial frequencies B, C, and F showed significant changes during the day, with the lowest v

SUBMITTER: Krolo I 

PROVIDER: S-EPMC11831931 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature