Sex-specific associations between dietary legume subtypes and type 2 diabetes in a prospective cohort study.

ABSTRACT:

Objectives

Dietary soy, known for its high phytoestrogen content, has been suggested to exhibit a sex-specific association with type 2 diabetes. However, evidence regarding the sex-specific associations of different legume subtypes with type 2 diabetes remains scarce. We aimed to evaluate whether habitual consumption of soy and non-soy legumes (beans and peanuts) was prospectively and sex-specifically associated with the risk of type 2 diabetes incidence, taking into considering significant sex-specific genetic factors beyond legume consumption.

Methods

A total of 16,666 participants (96,945 person-years) were followed and 945 incident cases were observed. Cumulative intake of legume subtypes was calculated using a food frequency questionnaire administered at baseline and du

SUBMITTER: Woo HW 

PROVIDER: S-EPMC11832243 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature