Comparative study of alpha-glucosidase inhibition of four Vietnamese medicinal plants <i>Combretum quadrangulare</i>, <i>Dicranopteris linearis</i>, <i>Psychotria adenophylla</i>, and <i>Garcinia schomburgkiana</i>: <i>In vitro</i> and <i>in vivo</i> studies.

ABSTRACT: Four medicinal plants C. quadrangulare, D. linearis, P. adenophylla, and G. schomburgkiana growing in the South of Vietnam were investigated for their alpha-glucosidase inhibition. The crude methanol extract of C. quadrangulare was determined to be the most active extract, then was selected for further in vivo assays including antidiabetic study and toxicity. In vitro alpha-glucosidase inhibition of four medicinal plants C. quadrangulare, D. linearis, P. adenophylla, and G. schomburgkiana was screened using standard procedures. In vivo antidiabetic activity, acute toxicity and subchronical toxicity of C. quadrangulare leaves was assessed on Swiss albino mice. Swiss albino mice were induced with diabe

SUBMITTER: Do TH 

PROVIDER: S-EPMC11832248 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature