Correlation study on gut microbiota and myosteatosis in patients with liver cirrhosis.

ABSTRACT:

Objective

To investigate the features of gut microbiota in cirrhotic patients with myosteatosis and identify specific bacterial species that may be involved in the pathogenesis of myosteatosis.

Methods

80 patients with liver cirrhosis were categorized into the myosteatosis group (n = 44) and the non-myosteatosis group (n = 36). Metagenomic sequencing was used to analyze the differences in gut microbiota composition between the two groups. Subsequently, the value of meaningful gut microbiota in the diagnosis of myosteatosis in patients with liver cirrhosis was analyzed.

Results

At the species level, however, 15 bacterial species exhibited significant differences in relative abundance between these two groups. The relative abundance of Roseburia hominis

SUBMITTER: Zhao N 

PROVIDER: S-EPMC11832399 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature