Baseline choroidal microvasculature dropout as a predictor of rapid global structural loss in open-angle glaucoma.

ABSTRACT: This study included 102 open-angle glaucoma (OAG) eyes with or without a localized choroidal microvasculature dropout (CMvD) at the inferior hemiretina, matched for age (≤ 10 years), axial length (≤ 1 mm), and visual field severity (≤ 1dB), and with a minimum 2-year follow-up. Serial thickness [circumpapillary retinal nerve fiber layer (cpRNFLT) and macular ganglion cell-inner plexiform layer thickness (mGCIPLT)], and vessel density (VD) [circumpapillary (cpVD) and macular VD (mVD)] parameters were obtained. The rate of change in each parameter at both the superior (CMvD-unaffected) and inferior (CMvD-affected) hemiretina were compared between matched eyes with (CMvD+) and without CMvD (CMvD-). Clinical factors associated with the rate of change in each parameter both globally and at the C

SUBMITTER: Lee A 

PROVIDER: S-EPMC11832928 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature