Early cardio-oncology intervention in thoracic radiotherapy: prospective single-arm pilot study.

ABSTRACT:

Background

While there is increasing recognition of the morbidity of cardiovascular disease in cancer survivors, including accelerated atherosclerosis following thoracic radiotherapy, patients are frequently under-optimized for cardiovascular risk.

Methods

In this prospective single-arm cohort pilot study, patients were treated with high-dose thoracic radiotherapy and had early consultation with cardio-oncology. Twenty patients were enrolled. The primary endpoint was adherence to cardio-oncology consultation. Secondary endpoints were cardiovascular medication intervention rate and patient-reported intervention perspectives. Clonal hematopoiesis of indeterminate potential, a major cardiovascular risk marker enriched in patients with cancer and induced by radiation exposure, w

SUBMITTER: Zhang SC 

PROVIDER: S-EPMC11833047 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature