Accuracy of blood heparin-binding protein (HBP) for diagnosis bacteremia in patients with sepsis.

ABSTRACT: Blood heparin-binding protein (HBP) for diagnosing bacteremia in patients with sepsis has not been fully investigated. This study aims to explore the diagnostic value of blood HBP in predicting bacteremia in patients with sepsis compared with procalcitonin (PCT), Interleukin 6 (IL-6), C-reactive protein (CRP), white blood count (WBC), and neutrophil. In this observational study, we enrolled consecutive 146 patients, who were divided into two groups as the bacteremia group (n = 57) and the control group (n = 89). HBP, PCT, IL-6, CRP, WBC, and neutrophil were measured. The Chi-squared test and Student's t-test were used to compare the baseline characteristics. The area under the receiver operating characteristic curve (AUC) was calculated to describe the diagnostic accuracy of the biomarkers

SUBMITTER: Mao Z 

PROVIDER: S-EPMC11833100 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature