Short-Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study.

ABSTRACT: The association between ambient ozone (O₃) and acute myocardial infarction (AMI) onset is unclear, particularly for younger patients and AMI subtypes. This study examined the short-term association of O₃ with AMI onset in patients aged 18-55 years and explored differences by AMI subtypes and patient characteristics. We analyzed 2,322 AMI patients admitted to 103 US hospitals (2008-2012). Daily maximum 8-hr O₃ concentrations estimated using a spatiotemporal deep learning approach were assigned to participants' home addresses. We used a time-stratified case-crossover design with conditional logistic regression to assess the association between O₃ and AMI, adjusting for fine particulate matter, air temperature, and relative humidity. We conducted st

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11833228 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature