Association of systemic inflammatory response index with all-cause and malignant neoplasm mortality in patients with gastrointestinal disease.

ABSTRACT:

Background

Apart from being a primary cause of morbidity and mortality globally, gastrointestinal (GI) disorders also contribute significantly to the cost of healthcare. In patients with GI diseases, the systemic inflammatory response index (SIRI) is not often used as a marker of systemic immune inflammation to assess mortality-associated risk from malignant neoplasms or all causes. Therefore, the objective of this study was to elaborate on the link between SIRI and all causes and malignant neoplasm mortality in patients with GI disorders.

Methods

Retrospective analysis was performed using National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2018. Restricted cubic spline (RCS) plots and multivariate Cox proportional hazards regression were used to exam

SUBMITTER: Wang P 

PROVIDER: S-EPMC11833371 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature