Head-to-head comparisons of risk discrimination by questionnaire-based lung cancer risk prediction models: a systematic review and meta-analysis.

ABSTRACT:

Background

While different lung cancer risk prediction models have been established as essential tools to identify high-risk participants for lung cancer screening programs, evaluations of their risk discriminatory performances have reported heterogenous findings in different research cohorts. We therefore aimed to summarise results of head-to-head comparisons of the predictive performance of various lung cancer risk models performed within the same study population.

Methods

In this systematic review and meta-analysis, we performed a systematic search of PubMed and Web of Science databases for primary studies published from inception to Oct 16, 2024. Articles comparing the performance of questionnaire-based lung cancer risk models in an independent, external validation cohor

SUBMITTER: Frick C 

PROVIDER: S-EPMC11833416 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature