Successful sperm retrieval by microdissection testicular sperm extraction in a man with partial AZFb deletion: a case report.

ABSTRACT:

Background

Y chromosome microdeletion is one of the major causes of male infertility, and obtaining mature spermatozoa in complete azoospermic factor (AZF)b deletion cases is difficult because germ cells maturation has arrested. However, there are very few reports on spermatogenesis in partial deletions of the AZFb region. We herein report a case of partial AZFb deletion in which sperm were successfully recovered by microdissection testicular sperm extraction (micro-TESE).

Case description

A 34-year-old man with cryptozoospermia was referred to Reproduction Center, Yokohama City University Medical Center. Both testicular sizes were normal, and the seminal tract had no abnormalities. Serum testosterone and follicle-stimulating hormone levels were also normal. The karyotype wa

SUBMITTER: Aoki S 

PROVIDER: S-EPMC11833528 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature