The U-shaped relationship between admission peripheral oxygen saturation and all-cause hospital mortality in acute exacerbation of chronic obstructive pulmonary disease: a retrospective analysis using the MIMIC III database.

ABSTRACT:

Background

Chronic obstructive pulmonary disease (COPD) and acute exacerbation of chronic obstructive pulmonary disease (AECOPD) pose global challenges, with oxygen saturation (SpO₂) levels crucial in evaluating mortality. This study explored the correlation between admission SpO₂ levels and all-cause hospital mortality in patients with AECOPD, assessing whether SpO₂ can serve as an independent risk factor for predicting in-hospital mortality in these patients.

Methods

This study involved 996 AECOPD patients sourced from the Medical Information Mart for Intensive Care (MIMIC) III database (version 1.3), with 134 fatalities. Patients were categorized into a death group (n=134) and a survival group (n=862). The average admission SpO₂

SUBMITTER: Meng N 

PROVIDER: S-EPMC11833588 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature