Hyponatremia Correction and Osmotic Demyelination Syndrome Risk: A Systematic Review and Meta-Analysis.

ABSTRACT:

Rationale & objective

Osmotic demyelination syndrome (ODS) is a rare but severe condition often attributed to the rate of sodium collection. We evaluated the association between the overly rapid sodium correction in adult hospitalized patients with ODS.

Study design

Systematic review and meta-analysis.

Setting & study populations

Adults hospitalized hyponatremia patients.

Selection criteria for studies

The studies comparing the incidence of ODS with and without rapid sodium correction inception to January 2024.

Data extraction

Two reviewers independently extracted data and assessed the risk of bias and the certainty of evidence.

Analytic approach

The incidence of ODS following a rapid and nonrapid sodium correction was pooled using the random effe

SUBMITTER: Suppadungsuk S 

PROVIDER: S-EPMC11833618 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature