The association between hospital volume and overall survival in adult AML patients treated with intensive chemotherapy.

ABSTRACT:

Background

Acute myeloid leukemia (AML) requires specialized care, particularly when administrating intensive remission induction chemotherapy (ICT). High-volume hospitals are presumed more adept at delivering this complex treatment, resulting in better overall survival (OS) rates. Despite its potential implications for quality improvement, research on the volume-outcome relationship in ICT administration for AML is scarce. This nationwide, population-based study in the Netherlands explored the volume-outcome relationship in AML.

Materials and methods

Data from the Netherlands Cancer Registry on adult (≥18 years of age) ICT-treated AML patients, diagnosed between 2014 and 2018, were analyzed. Hospital volume was assessed against OS using mixed-effects Cox regression, adjusti

SUBMITTER: Kaplan ZLR 

PROVIDER: S-EPMC11833631 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature