Incremental modelling and analysis of biological systems with fuzzy hybrid Petri nets.

ABSTRACT: Modelling biological systems depends on the availability of data and components of the system at hand. As our understanding of these systems evolves, the ability to gradually refine models by adding new components of different formalisms covering stochastic, discrete, deterministic, and uncertainty without starting from scratch becomes essential. However, there remains a significant gap in the availability of methodologies and tool support for incrementally modelling and analysing complex biological systems in a flexible and intuitive manner. In this paper, we employ fuzzy hybrid Petri nets as a powerful expressive tool for presenting an incremental modelling and analysis protocol of biological systems. We demonstrate the utility of our protocol through a case study on cholesterol and lipo

SUBMITTER: Assaf G 

PROVIDER: S-EPMC11833693 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature