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Association between blood heavy metals exposure with uterine fibroids among American women: a cross-sectional analysis from NHANES data.


ABSTRACT:

Background

Excessive exposure to heavy metals has been linked to various health problems, including organ damage, neurological disorders, and reproductive and developmental abnormalities. However, the relationship between heavy metals exposure and uterine fibroids remains uncertain. To explore this association, we conducted a cross-sectional study among American women.

Methods

We utilized data from three cycles of the National Health and Nutrition Examination Survey (NHANES, 1999-2006) to evaluate the association between uterine fibroids and blood heavy metal levels, including lead (Pb), cadmium (Cd), and mercury (Hg). Weighted logistic regression, restricted cubic spline (RCS), Bayesian kernel machine regression (BKMR), and subgroup analyse were used to examine the potentia

SUBMITTER: Yang Y 

PROVIDER: S-EPMC11834190 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature