Comprehensive analysis of long non-coding RNA and mRNA expression patterns during seminiferous tubules maturation in Guanzhong dairy goats.

ABSTRACT:

Background

Long non-coding RNAs (lncRNAs) play crucial roles in testicular development and spermatogenesis. The seminiferous tubule, the exclusive site of spermatogenesis, houses all types of male germ cells, regulated by both lncRNAs and mRNAs. However, the expression patterns and functions of these molecules across different developmental stages of dairy goat seminiferous tubules remain poorly understood.

Results

In this study, we sequenced and identified lncRNAs and mRNAs expressed in the seminiferous tubules of Guanzhong dairy goats at two developmental stages: 45-day-old premature (G45) and 240-day-old mature (G240). Significant differences in testis index and seminiferous tubules morphology were observed between G45 and G240 (P < 0.05). Transcriptome analyses revealed

SUBMITTER: Ren F 

PROVIDER: S-EPMC11834200 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature