Ultrasound-based quantitative microvasculature imaging for early prediction of response to neoadjuvant chemotherapy in patients with breast cancer.

ABSTRACT:

Background

Angiogenic activity of cancerous breast tumors can be impacted by neoadjuvant chemotherapy (NAC), thus potentially serving as a marker for response monitoring. While different imaging modalities can aid in evaluation of tumoral vascular changes, ultrasound-based approaches are particularly suitable for clinical use due to their availability and noninvasiveness. In this paper, we make use of quantitative high-definition microvasculature imaging (qHDMI) based on contrast-free ultrasound for assessment of NAC response in breast cancer patients.

Methods

Patients with invasive breast cancer recommended treatment with NAC were included in the study and ultrafast ultrasound data were acquired at pre-NAC, mid-NAC, and post-NAC time points. Data acquisitions also took plac

SUBMITTER: Sabeti S 

PROVIDER: S-EPMC11834208 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature