Investigation of the correlation between urinary aromatic amines and the risk of depression through an examination of the NHANES data from 2013 to 2014.

ABSTRACT:

Background

The relationship between aromatic amines (AA)s and depressive disorder remains elusive. The aim of this investigation was to examine the potential link between urinary AA levels and the likelihood of depression in American adults.

Methods

Through the analysis of data from 1175 participants in the 2013-2014 NHANES, our study delved into the association between urinary AA levels and the incidence of depression. Assessment of depression severity was conducted using the PHQ-9 questionnaire, alongside measuring levels of six urinary AAs. We explored this correlation in the overall population and various subgroups by employing a multivariable logistic model, restricted cubic spline (RCS) analysis, and a sensitivity analysis model while adjusting for potential confoundin

SUBMITTER: Zhu N 

PROVIDER: S-EPMC11834265 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature