Solid-supported polymer-lipid hybrid membrane for bioelectrochemistry of a membrane redox enzyme.

ABSTRACT: Hybrid membranes, consisting of phospholipids and amphiphilic block polymers, offer enhanced stability compared to liposomes and greater biocompatibility than polymersomes. These qualities make them a versatile platform for a wide range of applications across various fields. In this study, we have investigated the ability of solid-supported polymer-lipid hybrid membranes (SSHM) to act as a platform for bioelectrochemistry of membrane proteins. The redox enzyme, cytochrome bo ₃ (cyt bo ₃ ), a terminal oxidase in Escherichia coli, was reconstituted into hybrid vesicles (HVs), which were subsequently tested for their ability to form SSHMs on different self-assembled monolayers (SAMs) on gold electrodes. SSHM formation was monitored with

SUBMITTER: Catania R 

PROVIDER: S-EPMC11834424 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature