Value of a combined magnetic resonance-enhanced and diffusion-weighted imaging dual-sequence radiomics model in predicting the efficacy of high-intensity focused ultrasound ablation for uterine fibroids.

ABSTRACT:

Objective

To establish a joint radiomics model based on T1 contrast-enhanced (T1C) imaging and diffusion-weighted imaging (DWI), and investigate its value in predicting the efficacy of high-intensity focused ultrasound (HIFU) in ablating uterine fibroids.

Methods

This multicenter retrospective study included 195 patients with uterine fibroids. Their data were divided into training (n = 120), internal test (n = 30), and external test (n = 45) sets. The radiomic features were extracted from T1C and DWI sequences. Logistic regression was used to develop the T1C, DWI, integration, and joint models, and receiver operating characteristic curves were used to assess model performance. The Delong test was used to compare the predictive efficacies of different models, and the best mod

SUBMITTER: Huang X 

PROVIDER: S-EPMC11834504 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature