MoxR effects as an ATPase on anti-stress and pathogenicity of Riemerella anatipestifer.

ABSTRACT: Duck infectious serositis is a septicemic disease caused by the bacterium Riemerella anatipestifer (R. anatipestifer), which affects ducks, geese, turkeys, and other poultry. While outbreaks have been reported worldwide, the exact mechanisms of infection and disease progression remain unclear. Our previous research identified the two-component system PhoPR within the genome of R. anatipestifer and demonstrated its association with the bacterium's pathogenicity. Through multi-omics analysis, we found that PhoP directly regulates the expression of several genes, including moxR, within the Bacteroides aerotolerance (Bat) operon. However, the function of MoxR in R. anatipestifer has not yet been reported. To investigate the impact of MoxR on the expression of the bat operon and the pathogenici

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11834572 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature