Pseudocapsule thickness is positively associated with prognosis in patients with clear cell renal cell carcinoma.

ABSTRACT:

Background

Tumour pseudocapsule shows plasticity, whose representative indicator- pseudocapsule thickness- was little studied in clear cell renal cell carcinoma (ccRCC).

Methods

We enrolled 1037 ccRCC patients who underwent surgery between 2006 and 2013 at our institution. The patients did not receive therapy before surgery and were confirmed to have a pathological pseudocapsule. The associations of pseudocapsule thickness with overall survival and disease-free survival were studied using multivariable Cox regression analyses. Patients were stratified using points of maximum separation. Influential factors were examined with logistic regression.

Results

The average thickness was 0.47 mm (median: 0.43, interquartile range: 0.28-0.6). The average follow-up was 92.1. In

SUBMITTER: Xi W 

PROVIDER: S-EPMC11834655 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature