Immunolocalization and quantification of the phoenixin and GPR173 in the gastrointestinal tract of Holstein-Friesian bulls.

ABSTRACT: Phoenixin (PNX), well-conserved but newly discovered neuropeptide, is involved in various physiological processes, such as food intake, cardiovascular functions, reproductive functions, and stress regulation. PNX is the predicted ligand of GPR173 receptor, but due to its relatively recent discovery in 2013, there is a lack of studies describing the exact mechanism of action of the peptide. In addition, the protein was not been well-studied in specific organs, particularly in the gastrointestinal tract (GIT) of ruminants, including domestic cattle, which are among the world's main livestock animals. Therefore, this study aimed to investigate the immunolocalization and quantification of PNX and GPR173 in the GIT of domestic cattle. Study material, including GIT sections of two age groups, ca

SUBMITTER: Kras K 

PROVIDER: S-EPMC11834677 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature