Safety and efficacy of carbon dioxide laser therapy for vocal cord leukoplakia: A systematic review and meta-analysis.

ABSTRACT:

Background

Vocal cord leukoplakia is a precancerous lesion for which early surgical intervention following ineffective conservative treatment is the predominant approach. Carbon dioxide (CO2) laser treatment is a novel, minimally invasive therapy. However, there is insufficient evidence to suggest that CO2 laser treatment is superior to conventional surgical methods in terms of efficacy and safety. Therefore, this meta-analysis aimed to evaluate the efficacy and safety of CO2 laser treatment vs conventional surgical treatment for vocal cord leukoplakia.

Methods

A literature search was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines across 8 databases. Studies on the use of carbon dioxide laser therapy for vocal cord leukoplakia w

SUBMITTER: Liang J 

PROVIDER: S-EPMC11835110 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature