Successful lung transplantation in RPILD associated with anti-MDA5ab+: A case report.

ABSTRACT:

Rationale

Lung transplantation in rapidly progressive interstitial lung disease associated with antimelanoma differentiation-associated gene 5 antibody positive may be a rescue therapy in case of medical treatment failure and impossible weaning from the ventilatory support.

Patient concerns

A 59-year-old man with cough, expectoration, and fever for more than half a month, which aggravated with dyspnea for 4 days.

Diagnoses

Rapidly progressive interstitial lung disease was confirmed through chest high-resolution computed tomography and antimelanoma differentiation-associated gene 5 antibody positive.

Interventions

The patient was given extracorporeal membrane oxygenation and double lung transplantation.

Outcomes

The patient is currently undergoing rehabil

SUBMITTER: Zhang C 

PROVIDER: S-EPMC11835130 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature